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樓慧強,男,教授,博士生導師。

1 樓慧強 -教師簡介

  樓慧強,男,教授,博士生導師。
  2009年中國農業大學特聘教授,同年入選教育部「新世紀優秀人才和創新團隊」。
  主要以真核微生物釀酒酵母(Saccharomyces cerevisiae )為模式系統,在基因和蛋白相互作用網路水平探求基因組不穩定性的分子機理,及其與疾病/癌症發生的關係。目前致力於相互作用組學技術構建DNA複製期(即S期)的蛋白質調控網路。代表性論文包括Mol Cell封面文章等。

2 樓慧強 -學習與工作經歷

  2009.3- Professor, Department of Microbiology and Immunology,
  College of Biological Sciences, China Agricultural University.
  2006.8-2009.3 CIRM Senior Research Fellow,
  Divisions of Chemistry and Biology, California Institute of Technology, USA.
  2004.8-2006.8 Postdoctoral Scholar,
  Division of Chemistry and Chemical Engineering, California Institute of Technology, USA.
  1997.9-2004.2 Doctor of Philosophy,
  Institute of Microbiology, Chinese Academy of Sciences, China.
  1992.9-1997.7 Bachelor of Science,
  Department of Cell Biology and Genetics, Peking University, China.

3 樓慧強 -研究方向

  In budding yeast:
  Genome instability, Diseases and Cancer.
  DNA replication and the S phase checkpoint.
  DNA damage and replication stress signaling pathways.
  Asymmetric segregation and cell aging.
  In herperthermophilic archaea:
  Genome stability under boiling growth temperature.
  Epigenetic adaptation to the extremely harsh environment

4 樓慧強 -主講課程

  研究生課程
  《Progress in Microbiology》
  《Advanced Progress in Microbiology》
  《文獻研讀》

5 樓慧強 -發表文章

  Huiqiang Lou, Makiko Komata, Yuki Katou, Zhiyun Guan, Clara C. Reis, Martin Budd, Katsuhiko Shirahige, and Judith L. Campbell*. Mrc1 and DNA polymerase ε function together in linking DNA replication and the S phase checkpoint. Mol. Cell 2008, 32(1):106-117. (On the cover).
  [Previews] Labib Karim, Making Connections at DNA Replication Forks: Mrc1 Takes the Lead. Mol. Cell, 2008, 32(2):166-168.
  Huiqiang Lou, Zhenhong Duan, Tong Sun, and Li Huang*. Cleavage of double-stranded DNA by the intrinsic 3』-5』 exonuclease activity of DNA polymerase B1 from the hyperthermophilic archaeon Sulfolobus solfataricus at high temperature. FEMS Microbiol. Lett. 2004, 231: 111-117.
  Huiqiang Lou, Zhenhong Duan, Xiaofeng Huo, and Li Huang*. Modulation of hyperthermophilic DNA polymerase activity by archaeal chromatin proteins. J Biol. Chem. 2004, 279(1):127-32.
  Likui Zhang, Huiqiang Lou, et. al. Extremophile. Published online: 11 December 2009
  
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